Forbes D Porter Selected Research

Cyclodextrins

10/2019	2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease.
8/2017	Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Forbes D Porter Research Topics

Disease

44	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 04/2024 - 10/2010
37	Smith-Lemli-Opitz Syndrome 01/2024 - 04/2002
17	Disease Progression 11/2023 - 01/2010
16	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2023 - 11/2010
6	Lathosterolosis 07/2010 - 04/2003
3	Ataxia (Dyssynergia) 01/2022 - 01/2017
3	Inborn Genetic Diseases (Disease, Hereditary) 01/2022 - 12/2003
3	Lysosomal Storage Diseases (Lysosomal Storage Disease) 12/2019 - 11/2012
3	Intellectual Disability (Idiocy) 04/2010 - 04/2002
3	Desmosterolosis 09/2006 - 04/2003
2	Alzheimer Disease (Alzheimer's Disease) 12/2023 - 01/2012
2	Rare Diseases (Rare Disease) 08/2023 - 12/2016
2	Virus Diseases (Viral Diseases) 12/2022 - 01/2020
2	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 01/2022 - 01/2021
2	Hepatocellular Carcinoma (Hepatoma) 10/2021 - 10/2017
2	Autism Spectrum Disorder 01/2021 - 11/2020
2	Neuroinflammatory Diseases 12/2019 - 01/2014
2	Neoplasms (Cancer) 10/2015 - 01/2012
2	Inflammation (Inflammations) 01/2014 - 08/2012
2	Neurodevelopmental Disorders 10/2013 - 08/2013
2	Congenital Hemidysplasia with Ichthyosiform Erythroderma and Limb Defects 09/2006 - 07/2003
1	Amyloid Plaque 12/2023
1	Seizures (Absence Seizure) 10/2023
1	GM1 Gangliosidosis (Gangliosidosis GM1) 01/2023
1	Liver Failure 01/2023
1	Liver Diseases (Liver Disease) 01/2023
1	Congenital Disorders of Glycosylation 01/2023
1	Infections 12/2022
1	Cytokine Release Syndrome 12/2022
1	Human Influenza (Influenza) 12/2022
1	COVID-19 12/2022
1	Gliosis 05/2022
1	Iron Deficiencies 01/2022
1	Cerebellar Diseases (Cerebellar Syndrome) 12/2021
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 12/2021
1	Episodic Ataxia 12/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 10/2021
1	Sudden Death 10/2021
1	Autistic Disorder (Autism) 01/2021
1	Deglutition Disorders (Dysphagia) 12/2020

Drug/Important Bio-Agent (IBA)

61	CholesterolIBA 04/2024 - 04/2002
16	Biomarkers (Surrogate Marker)IBA 12/2023 - 01/2010
14	7-dehydrocholesterol reductaseIBA 10/2017 - 08/2003
13	LipidsIBA 01/2022 - 05/2006
8	SterolsIBA 01/2024 - 04/2003
8	Proteins (Proteins, Gene)FDA Link 01/2023 - 04/2010
5	7-dehydrocholesterolIBA 01/2017 - 04/2010
4	GlycosphingolipidsIBA 11/2021 - 01/2020
4	SphingolipidsIBA 12/2020 - 10/2013
4	miglustat (Zavesca)FDA Link 12/2020 - 01/2012
3	X-linked Creatine deficiencyIBA 10/2023 - 11/2020
3	Bile Acids and Salts (Bile Acids)IBA 01/2023 - 01/2016
3	EnzymesIBA 12/2019 - 08/2012
3	Simvastatin (Zocor)FDA LinkGeneric 01/2017 - 06/2005
3	lathosterol delta-5-dehydrogenase (lathosterol oxidase)IBA 07/2010 - 07/2003
2	OxysterolsIBA 01/2023 - 05/2009
2	Anesthetics (Anesthetic Agents)IBA 01/2023 - 12/2012
2	Niemann-Pick C1 ProteinIBA 12/2022 - 03/2014
2	Interleukin-10 (Interleukin 10)IBA 12/2022 - 01/2014
2	RNA (Ribonucleic Acid)IBA 12/2022 - 12/2019
2	CalciumIBA 01/2022 - 11/2015
2	Lysergic Acid Diethylamide (LSD)IBA 01/2022 - 12/2019
2	ApolipoproteinsIBA 01/2021 - 11/2012
2	CyclodextrinsIBA 10/2019 - 08/2017
2	beta-CyclodextrinsIBA 01/2018 - 01/2017
2	SteroidsIBA 10/2015 - 10/2002
2	Messenger RNA (mRNA)IBA 10/2015 - 01/2012
2	NeurosteroidsIBA 05/2009 - 01/2004
1	sterol O-acyltransferase 1IBA 04/2024
1	Peptides (Polypeptides)IBA 12/2023
1	Ubiquitin CIBA 11/2023
1	CreatineIBA 08/2023
1	Glycoproteins (Glycoprotein)IBA 12/2022
1	ChemokinesIBA 12/2022
1	Antiviral Agents (Antivirals)IBA 12/2022
1	Interleukin-6 (Interleukin 6)IBA 12/2022
1	CalbindinsIBA 05/2022
1	CytokinesIBA 01/2022
1	glycerylphosphoinositolIBA 01/2022
1	HepcidinsIBA 01/2022
1	Glycerophospholipids (Phosphoglycerides)IBA 01/2022
1	Ferritins (Ferritin)IBA 01/2022
1	IronIBA 01/2022
1	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 12/2021
1	Riluzole FDA LinkGeneric 12/2021
1	Glutamic Acid (Glutamate)FDA Link 12/2021
1	GangliosidesIBA 10/2021
1	HDL CholesterolIBA 01/2021
1	Apolipoproteins B (ApoB)IBA 01/2021
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2021
1	Muramidase (Lysozyme)IBA 11/2020
1	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2020
1	Proprotein Convertase 9IBA 03/2020
1	Toll-Like Receptor 3IBA 01/2020
1	Lysosomal Membrane ProteinsIBA 01/2020

Therapy/Procedure

16	Therapeutics 08/2023 - 03/2006
3	Anesthesia 01/2023 - 10/2002
1	Investigational Therapies (Experimental Therapy) 01/2022
1	Adjuvant Chemotherapy 10/2021
1	Activities of Daily Living (ADL) 01/2021